Current Issue - Silder
Current Issue: April 2023
This month's highlight articles
Wide-area transepithelial sampling with computer-assisted analysis to detect high grade dysplasia and cancer in Barrettʼs esophagus: a multicenter randomized study
Patients with Barrett’s esophagus (BE) and a history of dysplasia (n = 172) were randomly allocated in this multicenter randomized controlled trial to wide-area transepithelial sampling (WATS) followed by biopsies or vice versa. WATS as an adjunct to biopsies increased detection of high grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) (absolute increase of 10%); however, WATS alone did not detect more HGD/EAC than biopsies alone. The value of WATS as an alternative to biopsies is therefore limited in a BE population with dysplasia.
Evaluation of a real-time computeraided polyp detection system during screening colonoscopy: AI-DETECT study
In this randomized controlled trial, 614 patients were assigned to computer-aided detection (CADe) or standard colonoscopy. Colonoscopies were performed by eight screening-accredited colonoscopists in a bowel cancer screening program center. A borderline significant difference in polyp detection rate (79.7% vs. 85.7%; P=0.05) was found but no significant difference in adenoma detection rate (ADR; 65.0% vs. 71.4%; P=0.09). Use of CADe for improving ADR may be of limited value for screening-accredited colonoscopists with high ADRs.
Endoscopic submucosal dissection techniques and technology: European Society of Gastrointestinal Endoscopy (ESGE) Technical Review
This Technical Review from the European Society of Gastrointestinal Endoscopy (ESGE) is a companion to the recently updated Guideline on endoscopic submucosal dissection (ESD) for superficial gastrointestinal lesions. The Review addresses the technical aspects of ESD with a particular focus on the techniques and the technology/devices used during ESD, as well as the prevention and resolution of adverse events.
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Letter to the editor
Letter to the editor
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