Among 586 large nonpedunculated colorectal polyps (LNPCPs, ≥20mm), pre-resection biopsy (PRB) had a sensitivity of 21% for detecting high grade dysplasia. When the endoscopic mucosal resection (EMR) specimen showed cancer, PRB had only detected dysplasia. PRB was also associated with more submucosal fibrosis and intraprocedural bleeding. As PRB did not reliably detect advanced histology and may affect the EMR procedure, it should be used cautiously.

The exponential rise of obesity and the growing need for less invasive treatments form the basis of this paper. This is the first ESGE curriculum for training in bariatric endoscopy and the endoscopic treatment of bariatric surgical complications. The recommendations made here clarify how training in these fields should be provided in Europe.