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Current Issue January 2015

A novel approach to the diagnosis of pancreatic serous cystadenoma: needle-based confocal laser endomicroscopy (FREE ACCESS)

Bertrand Napoléon, Anne-Isabelle Lemaistre, Bertrand Pujol, Fabrice Caillol, Damien Lucidarme, Raphaël Bourdariat, Blandine Morellon-Mialhe, Fabien Fumex, Christine Lefort, Vincent Lepilliez, Laurent Palazzo, Geneviève Monges, Bernard Filoche, Marc Giovannini

In a 3-center study, French investigators evaluated the utility of needle-based confocal laser endomicroscopy in the diagnosis of 31 pancreatic cystic lesions. Serous cyst adenomas were found to have a typical superficial vascular network. This new sign was found to have high specificity and good interobserver agreement for the diagnosis of serous cyst adenomas when used by four independent observers.  Read more.

Intramuscular diclofenac for the prevention of post-ERCP pancreatitis: a randomized trial (FREE ACCESS)

Se Woo Park, Moon Jae Chung, Tak Geun Oh, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Si Young Song

A single, rectal dose of nonsteroidal anti-inflammatory drugs has been shown to reduce the incidence of post-ERCP pancreatitis. Whether intramuscular administration of these drugs has the same effect is debated. In this large, prospective study from Korea, 380 patients were randomized to receive either diclofenac or placebo by intramuscular injection immediately after the procedure. There was no difference in the incidence of post-ERCP pancreatitis between the groups, suggesting that prophylactic intramuscular diclofenac has no preventive effect on post-ERCP pancreatitis.  Read more.

A novel endoscopic weight loss therapy using gastric aspiration: results after 6 months (FREE ACCESS)

Henrik Forssell, Erik Norén

An endoscopic system for weight reduction consisting of a gastrostomy tube with a siphon assembly that aspirates approximately 30% of the ingested calories was assessed in obese participants. Of 25 subjects, 22 completed the study and had lost approximately 15% of their starting weight at the end of 6 months with two participants (10%) having complications that required hospital admission. Read more.