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Current Issue October 2014

Accuracy and concordance of endocytoscopic atypia for the diagnosis of gastric cancer  (FREE ACCESS)

Mitsuru Kaise, Ryusuke Kimura, Kosuke Nomura, Yasutaka Kuribayashi, Daisuke Kikuchi, Toshiro Iizuka, Yasuo Ohkura

Endocytoscopy using double staining with crystal violet and methylene blue detected high-grade endocytoscopic atypia in 78 % of gastric cancers (sensi-tivity) but in only 4 % of non-neoplastic lesions.  Read more.

Conventional vs. waterjet-assisted endoscopic submucosal dissection in early gastric cancer: a randomized controlled trial (FREE ACCESS)

Ping-Hong Zhou, Brigitte Schumacher, Li-Qing Yao, Mei-Dong Xu, Thomas Nordmann, Ming-Yan Cai, Jean-Pierre Charton, Michael Vieth, Horst Neuhaus

Endoscopic submucosal dissection (ESD) is technically challenging and time consuming. This randomized trial from China and Germany in patients with early gastric cancer shows that the new technique of waterjet-assisted ESD utilizing a hybrid knife required significantly fewer device exchanges and reduced procedure time compared with conventional ESD.  Read more.

Predictive factors for technically difficult endoscopic submucosal dissection in the colorectum   (FREE ACCESS)

Keisuke Hori, Toshio Uraoka, Keita Harada, Reiji Higashi, Yoshiro Kawahara, Hiroyuki Okada, Hemchand Ramberan, Naohisa Yahagi, Kazuhide Yamamoto

Endoscopic submucosal dissection (ESD) offers en bloc resection and may be curative in low risk submucosally invasive colorectal cancer. However it is not widely practised, largely because of technical difficulty and procedural risks. In a prospective observational study of 247 colorectal lesions, Japanese authors evaluated the risk factors for technical difficulty during ESD. Tumor size > 50mm, location at flexures, and scarring were all significant, their relevance substantially influenced by the experience of the endoscopist.  Read more.